Acute kidney injury detection using refined and physiological-feature augmented urine output
Over the past 3 decades, the incidence of AKI has increased over 20-fold, making it an important problem in critical care medicine. The purpose ofthis paper was to investigate the complex factors mediating the relationship between urine output and creatinine in AKI, and to develop a time varying multivariable model that identifies factors mediating the relationship based on augmentation of urine output with physiological features.